Virtual Makeover Software

NIH needs a makeover.

This elegantly carved jade face from Liangzhu in southeastern China provides an intriguing glimpse into the beliefs of the people who lived there from 3400 B.C.E. to 2250 B.C.E. As described in a special News Focus section beginning on page 930, discoveries at Liangzhu and other regions far from the traditional heartland of Chinese civilization are revealing surprisingly complex ancient culture...

Getting Healthier Through Microbiome Makeover

In this issue of EBioMedicine, Liping Zhao and colleagues show that children with obesity have similar gut microbiota dysbiosis regardless of their geneticmakeup,whether it is simple obesity (no underlying pathology) or genetic obesity (Prader–Willi syndrome). Furthermore, their microbiome profile can be changed by a 1-month dietary intervention. Interestingly, the authors also show that transf...

Chemical makeover inhibits IL-8

Chemical makeover inhibits IL-8 On page 2085, Proost et al. find that altering a single arginine turns an inflammatory chemokine docile. The chemokine IL-8, which activates and recruits neutrophils, is secreted as a mixture of isoforms that vary in length due to proteolysis. A cut after the first five amino end residues produces active protein, whereas cuts elsewhere inhibit activity. Proteolys...

Virtual but Visible Software

The problem of trying to view and comprehend large amounts of data is a well-known one. A specialised version of this problem, that of visualising program code (often known as software visualisation) has suffered from the field refusing to embrace new ideas and technologies. This paper presents an application of virtual reality to this problem and highlights areas of importance from virtual rea...

Extreme makeover for Hartford's print shop.